Spectrophotometric Determination of Nitrazepam Using Phloroglucinol as Coupling Reagent

Spectrophotometric Determination of Drugs Using Iodine As Analytical Reagent

Six drugs viz., Astemizole, Cisapride, Domperidone, Pantoprazole, Rabeprazole and Trazadone were tested for the formation of charge transfer complexes with Iodine. Each of these drugs turned the violet coloured i.e iodine , in CH2Cl2, to brown and exhibited a new band at 366nm in addition to the original band of iodine at 510nm due to anion of the reagent whose intensity increased with increase...

N-phenylbenzylamine as Novel Coupling Reagent for the Spectrophotometric Determination of Nitrite

This paper introduces a new reagent N-phenylbenzylamine for determination of nitrite in water and aqueous solutions. The reagent in the acidic medium coupled with diazotized dapsone to form the azo dye. The reaction provides a sensitive and reproducible determination of nitrite without special modifications of reaction conditions. The detection limit is 0.07 μg.ml, and linear range 0.1-2.0 μg.m...

Spectrophotometric determination of nitrate in polluted water using a new coupling reagent.

Facile Spectrophotometric Determination of Nimodipine and Nitrazepam in Pharmaceutical Preparations

abstract: A simple, accurate and sensitive visible spectrophotometric method for the determination of nimodipine (NMD) and nitrazepam (NTZ) is described. The method is based on the diazotization of reduced drugs with nitrous acid followed by coupling with resorcinol to form colored azo-dye in an alkaline medium. The resulting colored azo-dye exhibits maximum absorption peak at 480 nm for both N...

Spectrophotometric determination of Drugs & Pharmaceuticals Using Cerium(IV) as oxidant and Amaranth dye as analytical reagent

Simple, sensitive and accurate methods for determination of four drugs viz., Ciprofloxacin, Pantoprazole Sodium Sesquihydrate, Atrovastatin Calcium and Rosuvastine Calcium have been developed. The methods depend upon the oxidation of the drug by a known excess Ceric Ammonium Sulphate in sulphuric acid medium and subsequent determination of unreacted Ce (IV) using Amaranth dye. The methods have ...